郦鑫耀
郦鑫耀，教授，博导，xinyaoli@shu.edu.cn
课题组网站：https://www.x-mol.com/groups/xinyao_li
ORCID: https://orcid.org/0000-0001-5230-782X
研究领域：
近几年来一直致力于有机催化合成和理论计算研究，包括：1.不对称光催化反应；2.过渡金属催化环化反应；3.自由基参与的氧化反应；4. DFT理论计算研究氮化反应的自由基机理，环加成反应机理，过渡金属催化反应机理以及过渡金属光催化剂性能等。迄今已经在国际学术期刊Chem, J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Sci., Org. Lett.等上发表论文30余篇，论文他引1200余次。
教育经历：
2013.9‒2016.7 博士 北京大学 药物化学（导师：焦宁教授）
2007.9‒2013.7 学士，硕士 北京化工大学 应用化学（导师：许家喜教授）
工作经历：
2021.3‒至今 教授，博导 永利 永利化学系
2017.10‒2020.8 博士后 慕尼黑工业大学 有机化学（导师：Prof. Thorsten Bach）
2016.8‒2017.7 研究助理 北京大学 药物化学
主要奖励和荣誉:
2022年 Thieme Chemistry Journal Award国际学术奖
2021年 上海市海外高层次人才，浦江人才
2020年 北京市自然科学奖一等奖（排名8/8）
2017年 德国洪堡奖学金
2015年 北京大学学术类创新奖
2013年 北京市优秀毕业生
代表性科研项目：
1. 上海市海外高层次人才计划科研经费，2021.03-2024.03, 150万元，在研，主持
2. 上海市浦江(A类)人才计划，2021.10-2023.09, 30万元，在研，主持
3. 国家自然科学基金青年项目，2022.01-2024.12, 30万元，在研，主持
代表性学术论文：
1. Li, X. Y.; Großkopf, J.; Jandl, C.; Bach, T. Enantioselective Visible Light-mediated Aza-Paternò-Büchi Reactions of Quinoxalinones. Angew. Chem. Int. Ed. 2021, 60, 2684–2688.
2. Li, X. Y.; Kutta, R. J.; Jandl, C.; Bauer, A.; Nuernberger, P.; Bach, T. Photochemically Induced Ring Opening of Spirocyclopropyl Oxindoles: Evidence for a Triplet 1,3-Diradical Intermediate and Deracemization by a Chiral Sensitizer. Angew. Chem. Int. Ed. 2020, 59, 21640–21647. (Hot Paper)
3. Pan, J.;† Li, X. Y.;† Lin, F.; Liu, J.; Jiao, N. Chemoselective Nitrosylation of Anilines and Alkynes via Fragmentary or Complete NO Incorporation. Chem. 2018, 4, 1427–1442. (†These authors contributed equally.)
4. Liang, Y.-F.;† Li, X. Y.;† Wang, X. Y.; Zou, M. C.; Tang, C. H.; Liang, Y. J.; Song, S.; Jiao, N. Conversion of Simple Cyclohexanones into Catechols. J. Am. Chem. Soc. 2016, 138, 12271−12277. (†These authors contributed equally.)
5. Li, X. Y.; Li, X. W.; Jiao, N. Rh-Catalyzed Construction of Quinolin-2(1H)-ones via C−H Bond Activation of Simple Anilines with CO and Alkynes. J. Am. Chem. Soc. 2015, 137, 9246−9249.
6. Sun, X.;† Li, X. Y.;† Song, S.; Zhu, Y. C.; Liang, Y. F.; Jiao, N. Mn-Catalyzed Highly Efficient Aerobic Oxidative Hydroxyazidation of Olefins: A Direct Approach to β-Azido Alcohols. J. Am. Chem. Soc. 2015, 137, 6059−6066. (†These authors contributed equally.)
7. Chen, F.;† Huang, X. Q.;† Li, X. Y.;† Shen, T.; Zou, M. C.; Jiao, N. Dehydrogenative N-Incorporation: A Direct Approach to Quinoxaline N-Oxides under Mild Conditions. Angew. Chem. Int. Ed. 2014, 53, 10495–10499. (†These authors contributed equally.)
8. Wen, X. J.;† Li, X. Y.;† Luo, X.; Wang, W. J.; Song, S.; Jiao, N. Intramolecular Csp -H/C-C Bond Amination of Alkyl Azides for the Selective Synthesis of Cyclic Imines and Tertiary Amines. Chem. Sci. 2020, 11, 4482−4487. (†These authors contributed equally.)
9. Li, X. Y.; Pan, J.; Wu, H.; Jiao, N. Rh-catalyzed Aerobic Oxidative Cyclization of Anilines, Alkynes, and CO. Chem. Sci. 2017, 8, 6266−6273.
10. Li, X. Y.; Pan, J.; Song, S.; Jiao, N. Pd-catalyzed Dehydrogenative Annulation Approach for the Efficient Synthesis of Phenanthridinones. Chem. Sci. 2016, 7, 5384−5389 (ISACS19: Challenges in Organic Chemistry).
11. Li, X. Y.; Jandl, C.; Bach, T. Visible-Light-Mediated Enantioselective Photoreactions of 3 Alkylquinolones with 4 O Tethered Alkenes and Allenes. Org. Lett. 2020, 22, 3618−3622.
12. Li, X. Y.; Jandl, C.; Bach, T. Synthesis of Azocane- and Oxocane-annulated Furans by a [2+2] Photo-cycloaddition-Ring Opening Cascade. Synthesis 2021, 53, 723−730.
13. Li, X. Y.; Jiao, N. Reoxidation of Transition-metal Catalysts with O2. Chin. J. Chem. 2017, 35, 1349–1365.
14. Li, X. Y.;† Jin, X.;† Xu, J. X. Annuloselectivity in Reactions of Diacyl Dichlorides and Imines: Combined Experimental and Theoretical Studies. J. Org. Chem. 2015, 80, 6976−6985. (†These authors contributed equally.)
15. Hou, S.;† Li, X. Y.;† Xu, J. X. N[1,3]-sigmatropic Shift in the Benzidine Rearrangement: Experimental and Theoretical Investigation. Org. Biomol. Chem. 2014, 12, 4952−4963. (†These authors contributed equally.)
16. Li, X. Y.; Xu, J. X. DFT and Experimental Exploration of Intramolecular [2+2+2] Cycloaddition of Oxanorbornadienedicarboxylates and Analogues. J. Org. Chem. 2013, 78, 3039−3047.
17. Li, X. Y.; Xu, J. X. Annuloselectivity in Cycloadditions of Ketenes with Imines: A DFT Study. J. Org. Chem. 2013, 78, 347−355.
18. Li, X. Y.; Yang, Z. Y.; Xu, J. X. Comprehensive Theoretical Investigation on the Regioselectivity in the Nucleophilic Ring Opening of Epoxides. Curr. Org. Synth. 2013, 10, 169–177.
19. Li, X. Y.; Xu, J. X. Theoretical insights into the [4+2]/retro [4+2] cycloaddition approach to the synthesis of biaryls and polycyclic aromatics. Sci. China Chem. 2013, 56, 633–640.
20. Li, X. Y.; Xu, J. X. Theoretical Insights into the Metal-free and Formal [2+2+2] Cycloaddition Strategy via Intramolecular Cascade Propargylic ene/Diels–Alder Reactions with Tautomerization. Org. Biomol. Chem. 2011, 9, 5997–6003.
21. Qi, H. Z.;† Li, X. Y.;† Xu, J. X. Stereoselective Control in the Staudinger Reactions Involving Monosubstituted Ketenes with Electron Acceptor Substituents: Experimental Investigation and Theoretical Rationalization. Org. Biomol. Chem. 2011, 9, 2702–2714. (†These authors contributed equally.)
22. Li, X. Y.; Xu, J. X. Theoretical Calculational Investigation on the Regioselectivity of the Ring Opening of Thiiranes with Ammonia and Amines. Tetrahedron 2011, 67, 1681–1688.
23. Li, X. Y.; Xu, J. X. Abundant Intramolecular Ring Rearrangements of 1-(N-Benzyloxycarbonylamino)-arylmethylphos-phonate Phenyl monoesters Under Electrospray Ionization Conditions. Phosphorus, Sulfur, and Silicon, 2011, 186, 503–510.
24. Li, X. Y.; Chen, N.; Xu, J. X. An Improved and Mild Wenker Synthesis of Aziridines. Synthesis 2010, 20, 3423–3428.
25. Wang, W.; Li, X. Y.; Yang, X.; Ai, L.; Gong, Z.; Jiao, N.; Song S. Oxoammonium salts are catalysing efficient and selective halogenation of olefins, alkynes and aromatics. Nat. Commun. 2021, 12, 3873
26. Song S.; Li, X. Y.; Wei, J.; Wang, W.; Zhang, Y.; Ai, L.; Zhu, Y.; Shi, X.; Zhang, X.; Jiao, N. DMSO-catalysed late-stage chlorination of (hetero)arenes. Nat. Catal. 2020, 3, 107–115.
27. Huang, X.; Li, X. Y.; Xie, X.; Harms, K.; Riedel, R.; Meggers, E. Catalytic asymmetric synthesis of a nitrogen heterocycle through stereocontrolled direct photoreaction from electronically excited state. Nat. Commun. 2017, 8, 2245.
28. Huang, X. Q.; Li, X. Y.; Zou, M. C.; Song, S.; Tang, C. H.; Yuan, Y. Z.; Jiao, N. From Ketones to Esters by a Cu-Catalyzed Highly Selective C(CO)-C(alkyl) Bond Cleavage: Aerobic Oxidation and Oxygenation with Air. J. Am. Chem. Soc. 2014, 136, 14858–14865.
29. Li, X. W.; Lin, F.; Huang, K.; Wei, J.; Li, X. Y.; Wang, X.; Geng, X.; Jiao, N. Selective α-Oxyamination and Hydroxylation of Aliphatic Amides. Angew. Chem. Int. Ed. 2017, 56, 12307-12311.
30. Liu, J. Z.;† Wen, X. J.;† Qin, C.;† Li, X. Y.; Luo, X.; Sun, A.; Zhu, B.; Song, S.; Jiao, N. Oxygenation of Simple Olefins via Selective Allylic C-C Bond Cleavage: A Direct Approach to Cinnamyl Aldehydes, Angew. Chem. Int. Ed. 2017, 56. 11940-11944.
31. Huang, X. Q.; Li, X. Y.; Jiao, N. Copper-catalyzed Direct Transformation of Simple Alkynes to Alkenyl Nitriles via Aerobic Oxidative N incorporation. Chem. Sci. 2015, 6, 6355–6360.
32. Liang, Y. F.; Li, X. Y.; Wang, X. Y.; Yan, Y. P.; Feng, P.; Jiao, N. Aerobic Oxidation of PdII to PdIV by Active Radical Reactants: Direct C−H Nitration and Acylation of Arenes via Oxygenation Process with Molecular Oxygen. ACS Catal. 2015, 5, 1956−1963.
（最后更新日期：2022.2.16）
